This volume, written between May 3 and December 2, includes essays on mineralogy, the vegetable kingdom (such as botany and fruitification), and the animal kingdom (such as zoology, ornithology, and generation of animals).

These are primarily papers relating to the work of the United States Army Corps of Topographical Engineers, with special reference to surveys of harbors of the eastern United States. Some papers and letters relate to natural history and are addressed to John Lawrence LeConte. Correspondents include Rutherford B. Hayes, Joseph Henry, Daniel Parker, and E.G. Squier.

Nine of these letters are addressed to Sir Alexander Dick of Edinburgh (1763-1768), and relate to Morgan's medical studies, his travels on the Continent, and the founding of the medical department of the College of Physicians. These are copies of originals in possession of Mrs. Dick Cunyngham, Prestonfield House, Edinburgh. In addition there are letters from Morgan to: Petrus Camper, William Smith, Samuel Vaughan, Jr.; and from Peter Collinson to Camper; Camper to Morgan; S. Vaughan Jr. to Camper; and an exchange between Christian F. Michaelis and Camper. These concern Morgan, with mentions of fossils (mastodon bones in America), natural history, comments on Franklin, Jefferson, and Angelica Kauffmann. These are from originals in the Petrus Camper Papers, on deposit (1976) at the University of Amsterdam Library.

Benjamin Silliman (1779-1864, APS 1805) was a scientist and educator. As a professor of chemistry at Yale University from 1802 to 1853, and pioneering teacher of chemistry, mineralogy and geology, Silliman was largely responsible for the conversion of Yale College to Yale University, with strong medical and scientific departments.

Principal correspondents in the lettes of John Fries Frazer include Alexander Dallas Bache, Louis Agassiz, Joseph Henry, and Titian Ramsay Peale who discuss mainly general scientific topics, although personal and family matters are discussed with Bache. Topics include the University of Pennsylvania, boiler explosions, chemistry, education, the National Academy of Sciences, the Smithsonian Institution, fossils, magnetism, solar eclipses, the American Philosophical Society, weights and measures, the U.S. Coast and Geodetic Survey, scientific instruments, the American Civil War, electricity, the United States Mint, the Franklin Institute, scientists of the period, natural history, and publications.

This is a small but diverse collection documenting Wheatley's interests in mines and mining technology, paleontology, mineralogy, and shells. There are sketches of Wheatley's mine near Phoenixville, Pennsylvania; estimates of costs of machinery, and a list of furnace products sent to the Centennial Exposition.